Dominant negative mutant KRP protein protection of active cyclin-CDK complex inhibition by wild-type KRP

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United States of America Patent

PATENT NO 8742205
SERIAL NO

11460941

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Abstract

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Disclosed are mutant CDK inhibitor (CKI) polypeptides having dominant negative antagonist activity against wild-type CKI proteins, as well as related compositions, including nucleic acids and vectors encoding the mutant CKI polypeptides and transformed host cells and transgenic plants comprising such nucleic acids and vectors. Also disclosed are related methods for using the mutant proteins to modulate cell division in cells, particularly plant cells.

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TARGETED GROWTH INC2815 EASTLAKE AVENUE EAST SUITE 300 SEATTLE WA 98102

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DeRocher, Jay Bothell, US 7 39
Olivier, Paul Seattle, US 5 45
Roberts, James M Seattle, US 30 307

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