Inhibitors of protein tyrosine kinase activity

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United States of America Patent

PATENT NO 8729268
SERIAL NO

12920676

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Abstract

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This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and opthalmological diseases, disorders and conditions.

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Patent Owner(s)

Patent OwnerAddress
METHYLGENE INCMONTREAL QC H4S 2A1

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Claridge, Stephen William Montreal, CA 22 275
Gaudette, Frédéric Sherbrooke, CA 6 46
Isakovic, Ljubomir La Jolla, US 18 357
Kishida, Masashi Ako, JP 15 141
Mannion, Michael Montreal, CA 24 362
Raeppel, Stéphane St-Lazare, CA 10 72
Saavedra, Oscar Mario Montreal, CA 14 220
Uno, Tetsuyuki Okayama, JP 18 241
Vaisburg, Arkadii Kirkland, CA 56 936
Zhan, Lijie Montreal, CA 21 255

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