antagnistic activity

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United States of America Patent

PATENT NO 8729101
APP PUB NO 20090181949A1
SERIAL NO

12203113

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a group of novel 1H-imidazole derivatives, to methods for the preparation of these compounds, and to pharmaceutical compositions containing one or more of these compounds as an active component. These 1H-imidazole derivatives are potent cannabinoid-CB1 receptor agonists, partial agonists or antagonists, useful for the treatment of psychiatric and neurological disorders, as well as and other diseases involving cannabinoid neurotransmission. The compounds have the general formula (I), wherein R and R1-R4 have the meanings given in the specification.

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Patent Owner(s)

Patent OwnerAddress
SOLVAY PHARMACEUTICALS B VC J VAN HOUTENLAAN 36 NL-1381 CP WEESP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Herremans, Arnoldus H J Weesp, NL 7 39
Kruse, Cornelis G Weesp, NL 66 310
Lange, Josephus H M Weesp, NL 27 110
Van, Stuivenberg Herman H Weesp, NL 20 88

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