Display of disulfide linked dimeric proteins in filamentous phage
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United States of America Patent
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May 20, 2014
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Nov 15, 2010
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Nov 17, 2009
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Abstract
Methods are provided for the display of a complex homodimer protein on the surface of a bacteriophage particle and combinatorial synthetic libraries of such proteins displayed as a fusion polypeptide with filamentous phage pIX coat protein. Heterodimeric or more complex interchain bonded structure, such as disulfide-linked, multimeric proteins, may be displayed using the method of the invention.
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