Ligands for the GLP-1 receptor and methods for discovery thereof
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United States of America Patent
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May 6, 2014
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app pub date -
Apr 8, 2009
filing date -
Apr 9, 2008
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Abstract
Disclosed is the three-dimensional (3-D) structure of the GLP-1 receptor (GLP-1R) and methods by which the structure may be used to develop compounds that bind to, and/or modulate the GLP-1R. The technology described herein may be applied to the development of compounds that target the GLP-1R, or may be used to develop target compound that may bind to, and/or modulate the activity of the GLP-1R.
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