Polymorphic and amorphous salt forms of squalamine dilactate

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United States of America Patent

PATENT NO 8716270
SERIAL NO

13166911

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Abstract

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The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility in inhibiting neovascularization and endothelial cell proliferation.

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Patent Owner(s)

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ENTERIN INC2005 MARKET STREET SUITE 3125 PHILADELPHIA PA 19103

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  • 2011 Application Filing Year
  • A61K Class
  • 10915 Applications Filed
  • 8360 Patents Issued To-Date
  • 76.60 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201120122013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Armbruster, Kyle Douglassville, US 2 20
Chellquist, Eric Douglassville, US 3 22
Doubleday, Mary Snohomish, US 5 60
Gilbert, Charles W Pottstown, US 1 0
Levitt, Roy C Miami, US 20 118
McLane, Michael Lansdale, US 26 107
Zhang, Xuehai Ellicott City, US 15 87

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  • A61K Class
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  • 11 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1767499999127813872291511752101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500475050005250

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