Systems and methods for minimization or elimination of diffusion effects in a microfluidic system
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United States of America Patent
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Apr 29, 2014
Grant Date -
Apr 21, 2011
app pub date -
Apr 12, 2010
filing date -
Apr 10, 2009
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Abstract
The present invention relates to systems and methods for minimizing or eliminating diffusion effects. Diffused regions of a segmented flow of multiple, miscible fluid species may be vented off to a waste channel, and non-diffused regions of fluid may be preferentially pulled off the channel that contains the segmented flow. Multiple fluid samples that are not contaminated via diffusion may be collected for analysis and measurement in a single channel. The systems and methods for minimizing or eliminating diffusion effects may be used to minimize or eliminate diffusion effects in a microfluidic system for monitoring the amplification of DNA molecules and the dissociation behavior of the DNA molecules.
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