Epidermal growth factor receptor variants and pharmaceutical compositions thereof

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United States of America Patent

PATENT NO 8703917
SERIAL NO

13575432

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Abstract

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Provided are a novel Epidermal growth factor receptor variant-EGFRvA protein, a polynucleotide encoding the EGFRvA protein and a method of preparing the EGFRvA protein via recombination technology. Also provided is a uses of the polynucleotide encoding the EGFRvA protein. The EGFRvA protein has a function of promoting tumor cell invasion or promoting tumor cell migration.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI CANCER INSTITUTENO 25 LANE 2200 XIETU ROAD XUHUI DISTRICT SHANGHAI 200240 SHANGHAI CITY SHANGHAI CITY 200240

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gu, Jianren Shanghai, CN 12 37
Li, Zonghai Shanghai, CN 43 57
Pan, Xiaorong Shanghai, CN 1 4
Wang, Hai Shanghai, CN 243 3208
Yang, Shengli Shanghai, CN 14 40
Zhou, Min Shanghai, CN 195 1814

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