Biological function effecting viral vectors and chimeric cells useful as packaging cell lines and target cells

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8703480
SERIAL NO

09007123

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided are novel vectors comprising virus or viral portions in which biological function is effected by components on the surface or envelope. Biological function includes viral nucleic acid propagation and delivery in the same vector as well as other important functions such as enhanced target cell specificity and other favorable properties for endocytosis, nuclear localization, integration into the target cell genome and enhanced transduction efficiency functions. Also provided by this invention are chimeric cells useful as packaging cell lines or as target cells or even as both. By virtue of their unique sequences, such chimeric cells provide the machinery for viral nucleic acid propagation and packaging combined with other useful properties for delivering genetic information to any target cells of interest. Also provided are other vectors including those comprising initial nucleic acid wherein the initial nucleic acid has been modified and novel reconstituted vectors and fused vectors.

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Patent Owner(s)

Patent OwnerAddress
ENZO THERAPEUTICS INC527 MADISON AVENUE NEW YORK NY 10022

International Classification(s)

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  • 1998 Application Filing Year
  • A61K Class
  • 6684 Applications Filed
  • 2680 Patents Issued To-Date
  • 40.10 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances199819992000200120022003200420052006200720082009201020112012201320140255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Dakai Islip, US 45 195
Rabbani, Elazar New York, US 186 2785

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  • 1 Citation Count
  • A61K Class
  • 21.20 % this patent is cited more than
  • 11 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1767499999127813872291511752101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500475050005250

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11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 22, 2025