Composition exhibiting a von Willebrand Factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV

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United States of America Patent

PATENT NO 8703429
APP PUB NO 20090017467A1
SERIAL NO

12171934

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Abstract

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The invention relates to vWF cleaving entities having a molecular weight of 180 kD, 170 kD, 160 kD, 120 kD or 110 kD and an N-terminal amino acid sequence of AAGGILHLELLV, vWF cleaving complexes and methods for their production.

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Patent Owner(s)

Patent OwnerAddress
BAXALTA INCORPORATED1200 LAKESIDE DRIVE BANNOCKBURN IL 60015
BAXALTA GMBH8152 GLATTPARK OPFIKON

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Antoine, Gerhard Gross-Enzersdorf, AT 16 84
Furlan, Miha Bern, CH 16 124
Kerschbaumer, Randolf Klosterneuburg, AT 30 125
Laemmle, Bernhard Bolligen, CH 8 51
Schaller-Gerritsen, Helena Elisabeth Muri, CH 6 18
Scheiflinger, Friedrich Vienna, AT 107 597
Schwarz, Hans-Peter Vienna, AT 143 1170
Tagliavacca, Luigina Milan, IT 7 64
Turecek, Peter Klosterneuburg, AT 159 1387
Zimmermann, Klaus Pressbaum, AT 88 1100

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