Inducible gene expression
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United States of America Patent
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Apr 8, 2014
Grant Date -
Feb 10, 2011
app pub date -
Aug 3, 2005
filing date -
Aug 3, 2004
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Abstract
The invention relates to vector constructs for an HIV-specific gene therapy. The expression of transgenes is coupled with an infection of the cell with HIV while the transcription of the transgene is controlled by a transcription control region derived from HIV. In addition, the transgene is improved with regard to RNA stability and expression efficiency by modifying the nucleotide sequence.
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