Cell sorting system and methods
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United States of America Patent
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Apr 8, 2014
Grant Date -
Oct 23, 2008
app pub date -
Jul 23, 2007
filing date -
Apr 20, 2007
priority date (Note) -
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Abstract
Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on a switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of populations of small numbers of cells (i.e., 1000-100,000 cells). The invention includes packaging of the microfluidic channel network in a self-contained plastic cartridge that enables microfluidic channel network to macro-scale instrument interconnect, in a sterile, disposable format. Optical and/or fluidic switching forces are used alone or in combination to effect switching.
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