Montelukast 4-halobenzylamine salt and method for preparing montelukast sodium salt by using the same
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United States of America Patent
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Apr 1, 2014
Grant Date -
Jul 18, 2013
app pub date -
Dec 28, 2012
filing date -
Jul 30, 2010
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Abstract
Disclosed are a novel montelukast 4-halobenzylamine salt, and a method for preparing a montelukast sodium salt by using the same. In the disclosed method, a montelukast 4-halobenzylamine salt represented by Formula 2 or a montelukast sodium salt represented by Formula 1 is prepared by obtaining a compound represented by Formula 3 from a compound represented by Formula 5, in the same reactor, without an additional obtaining process.
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