Method of purifying a salt, sodium salt and disodium salt of pemetrexed

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United States of America Patent

PATENT NO 8686140
APP PUB NO 20100305319A1
SERIAL NO

12739576

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Abstract

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A method of purifying a salt of pemetrexed having a structure of formula (III) by salting-out, wherein if M3+ is H+, then each of M1+ and M2+ is independently H+, Li+, Na+ or K+, provided that both of them are not H+; if M3+ is Li+, Na+ or K+, then each of M1+ and M2+ is independently Li+, Na+ or K+.

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Patent Owner(s)

Patent OwnerAddress
CHONGQING PHARMACEUTICAL RESEARCH INSTITUTE CO LTD400061 NO 565 TU SHAN ROAD NAN'AN DISTRICT CHONGQING MUNICIPAL DISTRICT CHONGQING CITY 400061

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deng, Jie Chongqing, CN 62 1067
Lin, Bo Chongqing, CN 304 2667
Lin, Meng Chongqing, CN 23 101
Luo, Jie Chongqing, CN 108 397
Qin, Yongmei Chongqing, CN 3 7
Ye, Wenrun Chongqing, CN 4 8

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