Medical methods and agents for use therein
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United States of America Patent
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Apr 1, 2014
Grant Date -
Jan 3, 2013
app pub date -
Nov 17, 2010
filing date -
Nov 19, 2009
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Abstract
The present invention provides an immunomodulatory agent for use in the local treatment of tumors, wherein the treatment comprises patient-specific optimization of the dose of the immunomodulatory agent to identify the maximum therapeutic dose that does not induce an increase in the number of local regulatory T cells (Treg cells) in the patient The invention further provides methods for the local treatment of tumors as well as methods for optimising treatments for the same.
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