Activators and therapeutic applications thereof
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United States of America Patent
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Mar 25, 2014
Grant Date -
Jul 15, 2010
app pub date -
Jun 19, 2008
filing date -
Jun 20, 2007
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Abstract
The invention presents methods of identifying small molecule compounds that are activators of tumor suppressor protein p53 pathway, and its associated family members p63 and p73, function. The invention is further drawn to methods of killing tumor cells and treating cancers or other conditions requiring activation of the p53 family member pathways and DNA damage response pathways with the small molecules.
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