Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
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United States of America Patent
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Mar 25, 2014
Grant Date -
Oct 9, 2008
app pub date -
Feb 12, 2007
filing date -
Jun 20, 2002
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Abstract
The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition.
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