Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors

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United States of America Patent

PATENT NO 8673924
APP PUB NO 20080050384A1
SERIAL NO

11788847

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Abstract

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In its many embodiments, the present invention provides a method of inhibiting one or more cyclin dependent kinases in a patient comprising administering to said patient a therapeutically effective amount of at least one pyrazolo[1,5-a]pyrimidine compound or a pharmaceutical composition comprising such compound, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions. An example pyrazolo[1,5-a]pyrimidine compound useful in the present invention is shown below:

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alvarez, Carmen S Livingston, US 12 161
Bannerji, Rajat Morristown, US 1 19
Chan, Tin-Yau Edison, US 35 623
Dillard, Lawrence W Skillman, US 55 1025
Doll, Ronald J Convent Station, US 120 1796
Dwyer, Michael P Scotch Plains, US 55 1019
Fischmann, Thierry O Scotch Plains, US 18 198
Girijavallabhan, Viyyoor M Parsippany, US 127 1756
Guzi, Timothy J Chatham, US 71 1123
He, Zhenmin Shanghai, CN 3 28
Hobbs, Douglas Walsh Yardley, US 7 113
James, Ray Anthony Bensalem, US 14 174
Keertikar, Kartik M East Windsor, US 25 358
Kirschmeier, Paul Basking Ridge, US 9 45
Madison, Vincent S Mountain Lakes, US 43 467
Mallams, Alan Hackettstown, US 8 199
Paradkar, Vidyadhar M Somerville, US 9 97
Park, Haengsoon Plainsboro, US 16 263
Paruch, Kamil Garwood, US 58 995
Rivera, Jocelyn Monmouth Junction, US 5 113
Tran, Vinh D Fountain Valley, US 17 187

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