Synapse-specific proteins in glomeruli
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United States of America Patent
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Mar 18, 2014
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Sep 4, 2008
app pub date -
Dec 21, 2007
filing date -
Jul 1, 2005
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Abstract
The present invention identifies that glomeruli express many neuron-specific and especially synapse-specific protein similarities. In particular, the present invention identifies Rab3A expression, including the expression of altered forms, as well as expression of other synapse-specific proteins including neurotransmitter receptors. The invention further identifies that modulation of the activity of these synapse-specific proteins results in modulation of podocytes.
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