Solid dosage form for the ocular administration of an active principle, a soluble, solid ophthalmic insert and the production method thereof
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United States of America Patent
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Mar 4, 2014
Grant Date -
Jun 2, 2005
app pub date -
Dec 17, 2002
filing date -
Dec 18, 2001
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Abstract
A solid dosage form for the ocular administration of an active principle includes at least one biocompatible, water-soluble excipient for ophthalmic use. The form is obtained using a method which is selected from among the following: direct compression, dry compression, wet compression, compression of a lyophilizate, the compression being carried out a temperature below 45° C., or lyophilization, such that the form can disintegrate and release the active principle in the conjunctival sac. The invention also relates to an ophthalmic insert having the aforementioned dosage form which is appropriately dimensioned for ocular administration.
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