Nucleic acid constructs
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United States of America Patent
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Mar 4, 2014
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app pub date -
Oct 11, 2004
filing date -
Oct 10, 2003
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Abstract
A nucleic acid construct comprising a chimeric promoter sequence and a cloning site for insertion of a coding sequence in operable linkage with the chimeric promoter, wherein the chimeric promoter sequence comprises: (a) a hCMV immediate early promoter sequence; (b) exon 1 and at least a part of exon 2 of the hCMV major immediate early gene; and (c) a heterologous intron provided in place of the intron A region of the hCMV major immediate early gene.
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