8-methyl-1-phenyl-imidazol[1,5-a]pyrazine compounds as Lck inhibitors and uses thereof

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United States of America Patent

PATENT NO 8658794
APP PUB NO 20120309966A1
SERIAL NO

13577417

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Abstract

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The present invention provides 8-methyl-1-phenyl-imidazo[1,5-a]pyrazine derivatives according to formula I or pharmaceutically acceptable salts thereof. The compounds of the current invention show inhibitory activity against Lck and can be used for the treatment of Lck-mediated diseases or Lck-mediated conditions such as inflammatory disorders.

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MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
de, Man Adrianus Petrus Antonius Hurwenen, NL 22 69
Jans, Christiaan Gerardus Johannes Maria Cuijk, NL 22 124
Raaijmakers, Hans Cornelis Andreas Eindhoven, NL 1 21
Rewinkel, Johannes Bernardus Maria Berghem, NL 24 138
Wijkmans, Jacobus Cornelis Henricus Maria Oss, NL 2 23

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