Aqueous suspension preparations
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United States of America Patent
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Feb 25, 2014
Grant Date -
Oct 8, 2009
app pub date -
Jun 15, 2009
filing date -
Aug 25, 2000
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Abstract
Addition of polyvinylpyrrolidone and a water-soluble anionic macromolecular compound to an aqueous suspension of a hardly soluble drug allows to provide an aqueous suspension in which aggregation of drug particles, formation of macro crystals from suspended particles and formation of secondary particles from deposited particles are prevented, and adhesion and adsorption to containers made of plastics, e.g., polypropylene or polyethylene, are avoided. As it has a good redispersibility, the aqueous suspension is useful as eye drops, nasal drops, ear drops, injections, oral preparations, liniments and lotions.
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