Azaindole-indole coupled derivatives, preparation methods and uses thereof

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United States of America Patent

PATENT NO 8642765
APP PUB NO 20100137356A1
SERIAL NO

12663461

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A novel class of azaindole-indole coupled derivatives, their preparation methods, pharmaceutical compositions containing the same and the uses thereof. The common structural feature of these derivatives is that they are coupled by azaindole and indole bi-molecule at different positions, forming extended pi-conjugated systems. Such derivatives inhibited cell growth and proliferation by various mechanisms. The present compounds have improved solubility, increased bioavailability, and thus have enhanced drug actions, and reduced medical dosages and undesired responses.

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Patent Owner(s)

Patent OwnerAddress
JC (WUXI) COMPANY INCWUXI JIANGSU 214028

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Jingcai Wuxi, CN 8 90
Hua, Weiyi Wuxi, CN 1 2
Wang, Zhaohui Wuxi, CN 84 291
Yao, Qizheng Wuxi, CN 4 4

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