Controlled release complex composition comprising angiotensin-II-receptor blockers and HMG-CoA reductase inhibitors

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United States of America Patent

PATENT NO 8642083
APP PUB NO 20100074951A1
SERIAL NO

12513054

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Abstract

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Disclosed herein is a lag time delayed-release combination pharmaceutical composition comprising of an angiotensin-II-receptor blocker and an HMG-CoA reductase inhibitor, as well as a preparation method thereof. The composition is designed based on chronotherapy in which active ingredients are administered to have different onset times, such that the release of each active ingredient of the composition in body can be lag time delayed to a specific rate. Also, the composition is very effective for the treatment of hypertension and the prevention of complications in patients having metabolic syndromes which show diabetes, obesity, hyperlipidemia, coronary artery diseases and the like. More specifically, the composition is a drug delivery system designed such that the release of each drug is controlled to a specific rate, and it can show the most ideal effect, when it is absorbed in body.

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Patent Owner(s)

Patent OwnerAddress
HANALL BIOPHARMA CO LTD400-1 SANGSEO-DONG DAEDEOK-GU DAEJEON 306-120

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jo, Young Gwan Daejeon, KR 24 136
Jun, Sung Soo Seongnam-si, KR 39 261
Kim, Sung Wuk Seongnam-si, KR 51 282
Koo, Ja Seong Daejeon, KR 18 130
Son, Jae Woon Suwon-si, KR 8 94

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