dsRNA induced specific and non-specific immunity in crustaceans and other invertebrates and biodelivery vehicles for use therein
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United States of America Patent
Stats
-
Jan 21, 2014
Issued Date -
N/A
app pub date -
Jul 2, 2004
filing date -
Jul 2, 2003
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Methods for inducing systemic, non-specific and/or sequence specific immune responses in invertebrates, e.g., marine invertebrates such as mollusks, porifera, ctenophora, echinodermas, marine worms, cnideria and preferably crustaceans, by the administration of at least one dsRNA, that confers immunity against a pathogen, or modulates expression of gene that affects growth, reproduction, and general health or “robustness” are provided. Also provided are methods of identifying invertebrate genes, e.g., crustacean genes, the expression of which is involved in the induction of non-specific (systemic) immune responses against pathogens. Also disclosed are preferred delivery systems and methods for stably administering at least one dsRNA to a crustacean whereby the dsRNA is administered via injection, immersion, in a feed or nutrient medium or comprised in a microorganism, e.g., yeast or microalgae, that expresses said dsRNA and is ingestible by said crustacean, e.g., a shrimp.
First Claim
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Family
International Classification(s)
- 2004 Application Filing Year
- A61K Class
- 10035 Applications Filed
- 3484 Patents Issued To-Date
- 34.72 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 5 Citation Count
- A61K Class
- 21.20 % this patent is cited more than
- 11 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jul 21, 2025 |
