Methods for determining agents that treat or prevent obesity and/or obesity related diseases and methods for treatment therewith
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United States of America Patent
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Jan 21, 2014
Grant Date -
May 24, 2012
app pub date -
Nov 17, 2011
filing date -
Nov 22, 2010
priority date (Note) -
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Abstract
The present invention provides methods for determining a putative agent that treats or prevent obesity and/or obesity related diseases comprising contacting cells with the putative agent and measuring the activity and/or level of Maf1 and/or the activity and/or level of KIAA1875. The present invention also provides the agent identified by the methods herein and methods of treating or preventing obesity and/or obesity related diseases in a subject comprising administering to the subject a therapeutically effective amount of an agent that inhibits or downregulates Maf1 and/or activates or upregulates KIAA1875.
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