Cholesterol derivatives of inhibitors of viral fusion
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United States of America Patent
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Jan 14, 2014
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Dec 2, 2010
app pub date -
Oct 20, 2008
filing date -
Oct 22, 2007
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Abstract
The present invention relates to compounds comprising at least ten contigous amino acids of the HR2 domain of a Type 1 viral fusogenic protein of an enveloped virus, or a derivative thereof, attached at the C-terminal to cholesterol or a derivative thereof; or a pharmaceutically acceptable salt thereof which inhibit viral fusion. Thus compounds of the invention are useful to prevent or treat diseases caused by an enveloped virus.
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