Expression vector suitable for expression of a coding sequence for gene therapy
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United States of America Patent
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Jan 14, 2014
Grant Date -
Nov 8, 2012
app pub date -
Mar 19, 2012
filing date -
Feb 14, 2008
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Abstract
Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.
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