Fused pyrimidine-dione derivatives as TRPA1 modulators
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United States of America Patent
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Jan 7, 2014
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Feb 16, 2012
app pub date -
Mar 17, 2010
filing date -
Mar 23, 2009
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Abstract
The invention described herein relates to novel fused pyrimidinediones derivatives of formula (I) which are TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). This invention also provides processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.
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