Fosaprepitant dimeglumine intermediate, neutral fosaprepitant, and amorphous fosaprepitant dimeglumine and processes for their preparations

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United States of America Patent

PATENT NO 8623844
APP PUB NO 20110130366A1
SERIAL NO

13003885

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Abstract

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The present invention generally relates to a process for the preparation of fosaprepitant dimeglumine intermediate and its use in the preparation of fosaprepitant dimeglumine; to a neutral form of fosaprepitant in a solid state and processes for the preparation thereof; and to a stable amorphous fosaprepitant dimeglumine, having a stability at temperatures of about 2° C. to about 8° C. and at a relative humidity below at least 60%; and a process for the preparation thereof.

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Patent Owner(s)

Patent OwnerAddress
ALIVUS LIFE SCIENCES LIMITEDSOLAPUR 413213

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhatt, Navin Ganesh Navi Mumbai, IN 2 7
Khan, Mubeen Ahmed Navi Mumbai, IN 14 12
Khedekar, Mahesh Thane, IN 1 7
Sinha, Sukumar Navi Mumbai, IN 9 14
Trivedi, Nikhil Rasiklal Navi Mumbai, IN 4 7
Yadav, Ramjilal Navi Mumbai, IN 1 7

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