Methods for determining the retention of peptides in reverse phase chromatography using linear solvent strength theory

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United States of America Patent

PATENT NO 8620595
APP PUB NO 20110245461A1
SERIAL NO

13072877

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Abstract

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The present disclosure relates to methods for separating or isolating a peptide using reverse phase chromatography. The disclosure also relates to methods for calculating or determining the slope S of a peptide, wherein S is defined according to the Linear-Solvent-Strength equation log k=log k0−S*φ. Also provided are a set of peptides with known S values suitable for use in the described methods.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF MANITOBAROOM 202 ADMINISTRATION BUILDING WINNIPEG R3T 2N2

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Krokhin, Oleg V Winnipeg, CA 3 17
Spicer, Vic Winnipeg, CA 3 17

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