Cultured hematopoietic stem cells and method for expansion and analysis thereof
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United States of America Patent
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Dec 31, 2013
Grant Date -
Jun 9, 2011
app pub date -
Jul 6, 2010
filing date -
Oct 20, 2004
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Abstract
Hematopoietic stem cells and methods for ex vivo expansion of hematopoietic stem cells are provided. The methods comprise culturing the cells in a media containing an effective amount insulin-like growth factor(IGF), fibroblast growth factor (FGF), thrombopoietin (TPO), and stem cell factor (SCF), under conditions sufficient for expansion of said cells. Methods for identifying expanded hematopoeitc stem cells and kits for ex vivo expansion of hematopoietic stem cells are also provided.
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