GLP-1 analogues and their pharmaceutical salts and uses
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United States of America Patent
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Dec 24, 2013
Grant Date -
Aug 2, 2012
app pub date -
Jan 31, 2012
filing date -
Jul 30, 2009
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Abstract
This invention discloses GLP-1 analogues and their pharmaceutical salts, wherein the GLP-1 analogue comprises an amino acid sequence of general formula (I), wherein Lys represents a modified lysine with a lipophilic acid. The GLP-1 analogues provided by this invention have the function of human GLP-1, and a longer half-life in vivo compared with the human GLP-1. Uses of such compounds and compositions include treating non-insulin-dependent diabetes, insulin-dependent diabetes, and obesity.
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