Irritation-reducing ocular iontophoresis device
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United States of America Patent
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Dec 17, 2013
Grant Date -
Jul 7, 2011
app pub date -
Mar 8, 2011
filing date -
Apr 30, 2004
priority date (Note) -
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Abstract
The invention provides an ocular iontophoresis device for delivering medication, the device comprising a medication reservoir suitable for being positioned on the eye, at least one medication in solution in the reservoir, an active electrode disposed in the reservoir, and a passive electrode, the device including at least one medication dissolved in non-saline water, the said solution having a lying in the range 6.5 to 8.5, the medication having a pKa lying in the range about 5.5 to about 9.5 and includes an active principle which is associated with an additive, such as a dendrimer, a polymer, a nanoparticle, a microsphere, a liposome, or an emulsion, and having an ionic form of valency greater than or equal to 1.
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