Modified globin proteins with altered electron transport pathway
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United States of America Patent
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Dec 17, 2013
Grant Date -
Jun 3, 2010
app pub date -
Jun 26, 2008
filing date -
Jun 29, 2007
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Abstract
The present invention relates to a modified porphyrin-based oxygen-carrying protein, such as haemoglobin, which has been found, in its unmodified state to have a low affinity site of electron transfer and a high affinity electron transfer between a reductant and ferryl haem iron via one or more protein amino acids. The invention provides such proteins that comprise a modification to enhance this pathway.
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