Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation

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United States of America Patent

PATENT NO 8598359
APP PUB NO 20090163462A1
SERIAL NO

12136874

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The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ:

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DECODE GENETICS EHF101 REYKJAVIK

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Inventor Name Address # of filed Patents Total Citations
Bedell, Louis Prospect Heights, US 3 11
Gurney, Mark Grand Rapids, US 18 76
Mamat, Bjorn Freiburg, DE 3 21
Mishra, Rama K Chicago, US 31 210
Sandanayaka, Vincent Northboro, US 26 226
Singh, Jasbir Naperville, US 100 683
Yu, Peng Lisle, US 95 400
Zhao, Lei Naperville, US 382 2549

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