Derivatives of [1,3]Oxazin-2-one useful for the treatment of metabolic diseases such as lipid disorders
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United States of America Patent
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Dec 3, 2013
Grant Date -
Feb 16, 2012
app pub date -
Feb 3, 2010
filing date -
Feb 4, 2009
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Abstract
This invention relates to novel compounds of an 11 β-HSD1 inhibitor disclosed herein, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11/3-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell.
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