Recombinant adenovirus vector having a reduced side effect
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United States of America Patent
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Nov 26, 2013
Grant Date -
Jan 26, 2012
app pub date -
Jun 3, 2011
filing date -
May 26, 2000
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Abstract
The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.
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