by targeting cytolethal distending toxin
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Nov 19, 2013
Grant Date -
Oct 28, 2010
app pub date -
Aug 29, 2008
filing date -
Aug 31, 2007
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
An objective of the present invention is to provide the cytolethal distending toxin (CDT) of C. hyointestinalis and polynucleotides encoding it, and novel methods for detection of C. hyointestinalis using the cdt genes. The present inventors focused on the cytolethal distending toxin (CDT) of Campylobacter bacteria, and detected the cdt genes of a Campylobacter-like bacterium isolated from an enteritis patient in Thailand. The present inventors discovered a bacterial strain whose cdtB gene was amplified by common primers in C. jejuni, C. coli, and C. fetus, but not by multiplex PCR that can specifically detect the cdtA, cdtB, and cdtC genes of the three bacterial species. The bacterial strain was identified as C. hyointestinalis by 16S rRNA gene analysis. Furthermore, the entire nucleotide sequence of the cdt genes was determined by genome walking upstream and downstream of the cdtB gene.
First Claim
Other Claims data not available
Family
International Classification(s)
- 2008 Application Filing Year
- C07H Class
- 2142 Applications Filed
- 911 Patents Issued To-Date
- 42.54 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 1 Citation Count
- C07H Class
- 19.43 % this patent is cited more than
- 12 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | May 19, 2025 |
