Inhibitory RNA for modulating the molecular function of ZFAT gene
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United States of America Patent
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Nov 12, 2013
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Sep 29, 2011
app pub date -
Sep 8, 2008
filing date -
Sep 8, 2008
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Abstract
The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence.
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