Cyclodextrin-based polymers for therapeutics delivery

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United States of America Patent

PATENT NO 8580243
SERIAL NO

13769019

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.

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Patent Owner(s)

Patent OwnerAddress
CERULEAN PHARMA INC161 FIRST STREET CAMBRIDGE MA 02142

International Classification(s)

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  • 2013 Application Filing Year
  • A61K Class
  • 12711 Applications Filed
  • 11051 Patents Issued To-Date
  • 86.95 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Jianjun Arcadia, US 72 1305
Davis, Mark E Pasadena, US 255 5536
Khin, Kay T San Gabriel, US 20 261

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  • 3 Citation Count
  • A61K Class
  • 14.18 % this patent is cited more than
  • 12 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges93340159383591527830328862201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +025050075010001250150017502000225025002750300032503500375040004250

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