Thermostable neutral metalloproteases

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United States of America Patent

PATENT NO 8574884
SERIAL NO

13345547

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Abstract

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The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.

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Patent Owner(s)

Patent OwnerAddress
THE PROCTER & GAMBLE COMPANYONE PROCTER & GAMBLE PLAZA CINCINNATI OH 45202
DANISCO US INC925 PAGE MILL ROAD PALO ALTO CA 94304

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Estell, David A San Francisco, US 246 1784
Hommes, Ronaldus W J Haarlem, NL 11 58
Lee, Sang-Kyu Palo Alto, US 54 442
Oh, Hiroshi Cincinnati, US 48 288
Sadlowski, Eugene S Cincinnati, US 15 159
Shaw, Andrew San Francisco, US 137 1654
Wallace, Louise Menlo Park, US 21 128

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  • C07H Class
  • 19.43 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges3018731948631198115711301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050100150200250300350400450500550600650700750800850900950

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