Intermediate and process for preparing entecavir using same

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United States of America Patent

PATENT NO 8569490
APP PUB NO 20110251387A1
SERIAL NO

13140640

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Abstract

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The present invention relates to a novel, high-yield and low-cost method for preparing entecavir, [1-S-(1α,3α,4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, an antiviral agent, and novel intermediates used therein.

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Patent Owner(s)

Patent OwnerAddress
HANMI SCIENCE CO LTD214 MUHA-RO PALTAN-MYEON GYEONGGI-DO HWASEONG-SI 18536

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, Young-Kil Seoul, KR 26 70
Choi, Tae Jin Seongnam-si, KR 21 15
Kim, Cheol Kyung Suwon-si, KR 9 21
Kim, Jin Hee Hwaseong-si, KR 108 787
Lee, Gwan Sun Seoul, KR 69 722
Lee, Jaeheon Yongin-si, KR 26 88
Lee, Ji Eun Seoul, KR 149 758
Lim, Eun Jung Daegu, KR 47 146
Park, Chul Hyun Seongnam-si, KR 31 455
Park, Eun-Ju Hwaseong-si, KR 8 6
Park, Gha-Seung Yongin-si, KR 10 14

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