Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof

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United States of America Patent

PATENT NO 8563599
APP PUB NO 20110144195A1
SERIAL NO

12921013

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Abstract

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Two distinct methods are disclosed and claimed for synthesizing glyceollin I plus glyceollin II as a mixture and as their pure forms. Stereochemical isomers and various synthetic intermediates are also synthesized and claimed for their novel compositions of matter. All compounds and their mixtures are claimed for use in formulations that are useful to treat or prevent cancer, or that have utility as selective estrogen receptor modulators, such formulations including enhanced or medical foods, dietary supplements and ethical pharmaceutical agents.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE1400 INDEPENDENCE AVENUE SW WASHINGTON DC 20205

International Classification(s)

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  • 2009 Application Filing Year
  • A61K Class
  • 10313 Applications Filed
  • 6747 Patents Issued To-Date
  • 65.43 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances200920102011201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boue, Stephen M New Orleans, US 10 25
Burow, Matthew E New Orleans, US 20 20
Cleveland, Thomas E New Orleans, US 8 44
Erhardt, Paul W Toledo, US 48 197
Khupse, Rahul Toledo, US 1 1
McLachlan, John A New Orleans, US 3 5
Sarver, Jefferey G Toledo, US 1 0
Wiese, Thomas E New Orleans, US 3 5

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11.5 Year Payment $7400.00 $3700.00 $1850.00 Apr 22, 2025