Cell culture support and manufacture thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8557583
APP PUB NO 20080227203A1
SERIAL NO

12045847

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An object of the present invention is to provide a cell culture support making the detachment of a cell sheet easy as well as enabling the formation of a uniform cell sheet. The present invention relates to a method for manufacturing a cell culture support having a temperature responsive polymer immobilized onto the surface thereof via covalent bonding, the method including a coating step in which a composition including a monomer that can form the polymer by polymerization by radiation irradiation, an organic solvent and, in some cases, a prepolymer formed by polymerization of the monomer is coated onto the substrate having a surface containing a material which can be covalently bonded to the temperature responsive polymer by radiation irradiation to form a film on the surface of the substrate, a radiation irradiation step in which a polymerization reaction and a binding reaction between the substrate surface and the temperature responsive polymer are allowed to proceed by irradiating radiation to the film, and a drying step to dry the film.

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Patent Owner(s)

Patent OwnerAddress
DAI NIPPON PRINTING CO LTDTOKYO JAPAN
TOKYO WOMEN'S MEDICAL UNIVERSITYTOKYO 162-8666
CELLSEED INCTOKYO 135-0064

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akiyama, Yoshikatsu Tokyo, JP 14 146
Ashiba, Keisuke Tokyo, JP 1 4
Hagiwara, Kenichi Tokyo, JP 2 18
Okano, Teruo Tokyo, JP 109 1658
Shimizu, Tatsuya Tokyo, JP 160 1014
Watanabe, Hiroya Tokyo, JP 10 93
Watanabe, Masanao Tokyo, JP 25 178
Yamato, Masayuki Tokyo, JP 32 242

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