Screening method for the identification of agents capable of activating CD4+CD25+ regulatory T-cells through interactions with the HIV-1 GP120 binding site on CD4

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United States of America Patent

PATENT NO 8557533
APP PUB NO 20100074904A1
SERIAL NO

12525142

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Abstract

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The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.

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Patent Owner(s)

Patent OwnerAddress
ACTITREXX GMBHLANGENBECKSTRASSE 1 MAINZ 55131

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Becker, Christian Mainz, DE 45 150
Bopp, Tobias Aabergen, DE 4 5
Jonuleit, Helmut Ginsheim-Gustavsburg, DE 12 180
Schmitt, Edgar Mainz, DE 32 376
Schneider, Franz-Josef Laupheim, DE 6 16

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