Composite metastasis score with weighted coefficients for predicting breast cancer metastasis, and uses thereof
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Oct 15, 2013
Grant Date -
N/A
app pub date -
Feb 27, 2012
filing date -
Feb 25, 2011
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention relates to a composite metastasis score (“cMS”) based on expression of a 14-gene molecular signature (referred to as a metastasis score, or “MS”) in combination with progesterone receptor (PR) expression that is useful for predicting breast cancer metastasis. In preferred embodiments, the cMS is determined by applying weighted coefficients to MS and PR. The present invention provides methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information for predicting risk of breast cancer metastasis, among other embodiments.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully