7-substituted indirubin-3′oximes and their applications
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United States of America Patent
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Oct 8, 2013
Grant Date -
Dec 30, 2010
app pub date -
Dec 21, 2006
filing date -
Dec 23, 2005
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Abstract
The invention relates to new 3′-, 7-substituted-indirubins of formula (I) wherein R represents N—OH, N—O-alkyl or N—O—CO-alkyl, NO—(Ra)n1-Het, N—O—(Y)n1—N Ra Rb, N—O—CO—N(Rb Rc), radical with Het representing an aliphatic nitrogeneous heterocycle, Y being an optionally substituted —CH2— radical, n1 being 1 to 3, and X is an halogen atom selected in the group comprising F, Cl, Br, I, and Z is H or CH3 and the salts thereof.
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