Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells
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United States of America Patent
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Oct 8, 2013
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app pub date -
Feb 27, 2012
filing date -
Nov 30, 2007
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Abstract
The invention provides novel methods of reducing transplant rejection and cardiac allograft vasculopathy in humans by employing the implantation of autologous progenitor cells into the transplanted donor heart. The autologous progenitor cells can be vascular progenitor cells (VPCs) and/or myocyte progenitor cells (MPCs) isolated from the recipient's explanted heart. Alternatively, bone marrow progenitor cells (BMPCs) isolated from the recipient may also be used.
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